Molecular Ecology

Local adaptation represents the first step to speciation and therefore to biological diversification. Elucidating the genetic mechanisms underlying this process therefore constitutes a key question in the field of evolutionary biology. Mutations as well as chromosome rearrangements have been shown to be involved in this evolutionary process. However, to what extent other sources of genetic variation influence the evolution of natural populations remains poorly understood. To this regard, the aim of our project is to better understand how transposable element activation contributes to the evolution of natural populations, using Brachypodium distachyon as a model.

• Identification of specificity-defining amino acids of the wheat immune receptor Pm2 and powdery mildew effector AvrPm2
  Manser, Beatrice; Koller, Teresa; Praz, Coraline Rosalie; Roulin, Anne C.; Zbinden, Helen; Arora, Sanu; Steuernagel, Burkhard; Wulff, Brande B. H.; Keller, Beat; Sanchez-Martin, Javier
  Plant Journal  10.1111/tpj.15214  Early Access: APR 2021
• Population genomics and haplotype analysis in spelt and bread wheat identifies a gene regulating glume color
  Abrouk, Michael; Athiyannan, Naveenkumar; Mueller, Thomas; Pailles, Yveline; Stritt, Christoph; Roulin, Anne; Chu, Chenggen; Liu, Shuyu; Morita, Takumi; Handa, Hirokazu; Poland, Jesse; Keller, Beat; Krattinger, Simon G.
  Communications Biology,  10.1038/s42003-021-01908-6  MAR 19 2021
• Impact of Transposable Elements on Methylation and Gene Expression across Natural Accessions of Brachypodium distachyon
  Wyler, Michele; Stritt, Christoph; Walser, Jean-Claude; Baroux, Celia; Roulin, Anne C.
  Genome Biology And Evolution,  10.1093/gbe/evaa180 NOV 2020
• Genetic and Methylome Variation in Turkish Brachypodium distachyon Accessions Differentiate Two Geographically Distinct Subpopulations
  Skalska, Aleksandra; Stritt, Christoph; Wyler, Michele; Williams, Hefin W.; Vickers, Martin; et al.
  International Journal Of Molecular Sciences   DOI: 10.3390/ijms21186700  SEP 2020
• Diversity, dynamics and effects of long terminal repeat retrotransposons in the model grass Brachypodium distachyon
  Stritt, Christoph; Wyler, Michele; Gimmi, Elena L.; Pippel, Martin; Roulin, Anne C.
  New Phytologist,  DOI: https://doi.org/10.1111/nph.16308, DEC 2019
• Genome-wide scans of selection highlight the impact of biotic and abiotic constraints in natural populations of the model grass Brachypodium distachyon
  Bourgeois, Y; Stritt, C; Walser, JC; Gordon, SP; Vogel, JP; Roulin, AC
  PLANT JOURNAL, 96 (2):438-451; 10.1111/tpj.14042 OCT 2018
• Recent Activity in Expanding Populations and Purifying Selection Have Shaped Transposable Element Landscapes across Natural Accessions of the Mediterranean Grass Brachypodium distachyon 
  Stritt, Christoph; Gordon, Sean P.; Wicker, Thomas; et al. 
  GENOME BIOLOGY AND EVOLUTION, 10 (1): 304-318 10.1093/gbe/evx276 JAN 2018
• Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure 
  Gordon, Sean P.; Contreras-Moreira, Bruno; Woods, Daniel P.; et al. 
  NATURE COMMUNICATIONS, 8: 10.1038/s41467-017-02292-8 DEC 19 2017
• Parasitism drives host genome evolution: Insights from the Pasteuria ramosa-Daphnia magna system 
  Bourgeois, Yann; Roulin, Anne C; Mueller, Kristina; et al. 
  EVOLUTION, 71 (4): 1106-1113 APR 2017
• …

• Genome evolution
• Transposable elements
• Local adaptation
• Genetic diversity

• Population genomics
• Ecology
• Bio-informatics