Methylome dynamics during Arabidopsis reproduction
Reproduction is a key step in any organism's life cycle and its success relies on complex gene regulation. The fusion of highly specialized cells, the gametes, generate a totipotent embryo. We are studying the molecular mechanisms that regulate epigenetic marks, especially DNA methylation, transmission during sexual reproduction in the model plant Arabidopsis thaliana. As epigenetic marks can be modified by environmental factors, it is important to understand how DNA methylation is stably maintained while still allowing diversity in plants and other sexual organisms.
- A complex of Arabidopsis DRB proteins can impair dsRNA processing
Tschopp, Marie-Aude; Iki, Taichiro; Brosnan, Christopher A.; Jullien, PE; Pumplin, N
RNA 23(5):782-797, 10.1261/rna.059519.116 MAY 2017
- DNA Methylation Influences the Expression of DICER-LIKE4 Isoforms, Which Encode Proteins of Alternative Localization and Function
Pumplin, Nathan; Sarazin, Alexis; Jullien, Pauline E.; et al.
PLANT CELL, 28 (11): 2786-2804, https://doi.org/10.1105/tpc.16.00554 NOV 2016
- DNA Methylation Dynamics during Sexual Reproduction in Arabidopsis thaliana
Jullien, Pauline E.; Susaki, Daichi; Yelagandula, Ramesh; et al.
CURRENT BIOLOGY 22(19):1825-1830, 10.1016/j.cub.2012.07.061 OCT 9 2012
- Reprogramming of DNA Methylation in Pollen Guides Epigenetic Inheritance via Small RNA
Calarco, Joseph P.; Borges, Filipe; Donoghue, Mark T. A.; et al.
CELL 151(1):194-205, 10.1016/j.cell.2012.09.001 SEP 28 2012
- DNA methylation reprogramming during plant sexual reproduction?
Jullien, Pauline E.; Berger, Frederic
TRENDS IN GENETICS 26(9):394-399, 10.1016/j.tig.2010.06.001 SEP 2010