Cereal biotechnology research for crop improvement
Cereals, such as rice and wheat, are important source of food worldwide but they contain very low levels of bioavailable micronutrients (such as iron and zinc) for a balanced human diet. Thus, micronutrient malnutrition is a serious global health challenge. Biofortification of edible plant parts has been proposed as the most relevant options to combat micronutrient malnutrition. In our group, we contribute towards cereal biofortification through biotechnological approaches.
Furthermore, plants are known to maintain metal ion homeostasis through sophisticated mechanisms that tightly control the acquisition and distribution of metal ions to the specific compartments and for storage. We study the molecular mechanisms underlying micro-nutrient composition in the cereal grains, focusing on zinc and iron. These metal homeostasis studies are expected to provide novel insights into molecular and agronomic aspects of plant biofortification of essential micro-nutrients.
In addition to engineering for micronutrient traits, we are interested in screening of cereal germplasm for novel stress related traits (including drought tolerance in rice and resistance to rice blast). It is of utmost importance for crop breeding to uncover the underlying genetic components from un-adapted germplasm that have poor agronomic performance but stronger tolerance mechanisms against biotic and abiotic stresses. Subsequent transfer of these genetic components to elite high-yielding varieties will allow closing yield gaps, ultimately contributing towards food security.
- Facilitated citrate-dependent iron translocation increases rice endosperm iron and zinc concentrations
Wu, Ting-Ying; Gruissem, Wilhelm; Bhullar, Navreet K.
PLANT SCIENCE, 270 13-22; https://doi.org/10.1016/j.plantsci.2018.02.002 MAY 2018
- Iron biofortification in the 21st century: setting realistic targets, overcoming obstacles, and new strategies for healthy nutrition
Vasconcelos, Marta W.; Gruissem, Wilhelm; Bhullar, Navreet K.
CURRENT OPINION IN BIOTECHNOLOGY, 44: 8-15 https://doi.org/10.1016/j.copbio.2016.10.001 APR 2017
- Rice NICOTIANAMINE SYNTHASE 2 expression improves dietary iron and zinc levels in wheat
Singh, Simrat Pal; Keller, Beat; Gruissem, Wilhelm; et al.
THEORETICAL AND APPLIED GENETICS, 130 (2): 283-292 FEB 2017 Article (Details)
- Enhanced Grain Iron Levels in Rice Expressing an IRON-REGULATED METAL TRANSPORTER, NICOTIANAMINE SYNTHASE, and FERRITIN Gene Cassette
Boonyaves, Kulaporn; Wu, Ting-Ying; Gruissem, Wilhelm; et al.
FRONTIERS IN PLANT SCIENCE, 8: FEB 7 2017 Article (Details)
- Geographically Distinct and Domain-Specific Sequence Variations in the Alleles of Rice Blast Resistance Gene Pib
Vasudevan, Kumar; Vera Cruz, Casiana M.; Gruissem, Wilhelm; et al.
FRONTIERS IN PLANT SCIENCE, 7: JUN 23 2016 Article (Details)
- NOD promoter-controlled AtIRT1 expression functions synergistically with NAS and FERRITIN genes to increase iron in rice grains
Boonyaves, Kulaporn; Gruissem, Wilhelm; Bhullar, Navreet K.
PLANT MOLECULAR BIOLOGY, 90 (3): 207-215 FEB 2016 Article (Details)
- Micronutrient biofortification of cereals
- Metal homeostasis in plants
- Plant biotic and abiotic stresses
- Allele/gene mining from genetic resources
- Molecular basis of plant metal homeostasis
- Crop improvement and molecular plant breeding